Join the AMBER Research Project’s e-LEAP! Do you have personal experience of depression or work with/care for those who do? We’re looking for people to…
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AMBER : Antidepressant Medications: Biology, Exposure & Response Posts
This short animation uses a simple shopping bag analogy to explain the science behind personalised medicine. AMBER research is focused on identifying the key genetic…
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Researchers used data from over 71,000 health records to help identify a definition for treatment-resistant depression (TRD). They found that 2+ switches between antidepressants and/or…
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In this blog post, we explore how researchers detect small genetic variations between individuals and bring them together into a single score. We’ll also look…
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Researchers used computer technology to gather together clinical trial data from the US and EU and identify which ones had collected blood samples or genetic…
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Researchers identified a DNA pattern in one dataset and used it to predict antidepressant response in another dataset. Although it is early days, this finding…
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Researchers found that people who switched from an SSRI to another type of antidepressant had similar genetic patterns to those who didn’t get better in…
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Understanding mental health—and the many factors that influence it—requires large amounts of detailed information. To help with this, researchers in Scotland created a new project…
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Depression affects millions of people worldwide, and while medications called antidepressants can help, they don’t work for everyone. In fact, only about one-third of people…
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June 2025 saw the second in person all AMBER meeting since the project began. This year it was the turn of University of Edinburgh to…
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In this first of three posts, AMBER researchers explain some of the background to the project, including some of the things we already know and…
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