No piece of art deserves the sacrifice of one’s sanity in order to be created.
As we discussed in many other classes, you should always try your best to plan as much as possible during pre-production process. Inventiveness and improvisation are essential to the craft of filmmaking, but one should always make the shoot as comfortable as possible. To rewrite your script in the middle of production sounds like a big no-no to me. If you are unsure whether something works, spend more time on it before jumping into the action.
And even if something you created achieves cult status, it doesn’t justify all the questionable choices made along the way.